Homeopathic Medical Marijuana Tincture.
in an alcohol base.
does NOT have THC.
THC is the psychoactive cannabinoid that give the "high" feeling.
This fact makes SibinnaK Brand Homeopathic Medical Marijuanna
legal in virtually every state.
Although there is no detectable THC in this product, the precursor THCA is present. There is no psychoactive effect, however it is possible that a urine test may test positive. Those who are in employment. and other relationships where testing is required should not use this product.
Calc Max Total Cannabinoids is the sum of Total THC, Total CBD, CBN, CBG, CBC, THCV, and CBDV. Sample tested 209.8 total Cannabinoids. No THC detected.
Research strongly suggests that cannabinoids found in Marijuana may be useful in treating a variety of ailments namely glaucoma, pain, nausea, muscle spasms and loss of appetite. It is also being investigated in cancer patients as a way to alleviate the side effects of cancer therapy, but some laboratory tests are also investigating anti-tumor properties.
Cannabinoids such as THC have been shown in numerous animal studies to increase food consumption and some human trials have also shown positive results. For example, a study comparing THC with a placebo in cancer patients found that those taking THC had a better appetite and sense of taste and although they didn’t consume more calories they felt more relaxed and had a better quality of sleep compared to the placebo group. Another study investigating the FDA-approved synthetic cannabinoid (THC) drug dronabinol in HIV/AIDS patients presenting weight loss found that those taking THC ate more than controls and stopped losing weight. However, in a study comparing dronabinol with a standard drug (megestrol) in cancer patients presenting loss of appetite, researchers found that dronabinol was not as effective as megestrol in increasing appetite or weight gain.
No surprises here, but a study in healthy people found that those inhaling marijuana consumed more calories (had “the munchies”), especially from fatty and sugary snacks, than those inhaling a placebo.
How does it stimulate appetite? The CB1 receptor is active in numerous areas of the body that are known to stimulate eating behavior, such as the hypothalamus and limbic forebrain, and also certain areas in the stomach and intestine. THC can exert effects by mimicking endogenous substances (called endocannabinoids) that are naturally found in the body.
Nausea and Vomiting
There have been numerous studies investigating the ability of cannabinoids to reduce and nausea and vomiting associated with chemotherapy. A 2001 systematic review of 30 studies involving synthetic cannabinoids (dronabinol, nabilone or levonantradol) compared with a placebo or an active control (a non-cannabinoid drug) found that the cannabinoids were more effective than the active control or the placebo at reducing vomiting and nausea. Furthermore, patients demonstrated a preference for the cannabinoid drugs over the placebo and the active control drugs, and they presented limited side-effects.
How do they work? The endocanabinoid system (the name for the group of molecules and receptors such as CB1 and CB2 that are collectively involved in a variety of physiological processes and mediating the psychoactive effects of marijuana) is key to modulating numerous systems such as reward pathways, pain perception and emesis (vomiting). Areas of the brain involved in chemotherapy induced vomiting are higher cortical and limbic regions that can influence the stimulation or suppression of nausea ( the feeling that you may puke) and vomiting. CB1 receptors are found in high quantities in these areas.
While synthetic marijuana drugs like Nabilonen, Marinol or Dronabinol are yet to be approved by FDA for pain management, a few studies have shown that they may be beneficial. For example, a small 2010 study carried out by McGill University Health Center investigated 21 adults with post-traumatic or postsurgical neuropathic pain. Participants were randomly assigned to receive cannabis at 4 potencies (0%, 2.5%, 6% or 9.4% THC) which was smoked at home three times a day. All participants used all four potencies, which were rotated throughout the duration of the study. Participants recorded pain intensity and also mood, sleep and quality of life. They found that cannabis smoked at a concentration of 9.4% THC moderately reduced pain and improved sleep, with few side-effects. This is a preliminary finding and larger studies are needed to verify these results.
A 2007 study carried out by researchers from the University of California at San Francisco looked at HIV patients with peripheral neuropathy and found that a significantly higher number of patients receiving the treatment (smoking marijuana) experienced a reduction in pain compared with the placebo group.
is a condition caused by an increase in pressure within the eye which can lead to blindness if left untreated. It is thought that Certain Cannabinoids effectively lower intralocular pressure (IOP), by increasing ocular blood flow through their vasorelaxant properties, accordingly there have been a few studies since the 1970’s investigating cannabis as a possible treatment for glaucoma. For example, an early and small trial in 1971. demonstrated that smoking marijuana reduced IOP but the effects only lasted 3-4 hours, limiting its usefulness when taken in this manner. However, studies have shown that while marijuana may temporarily reduce IOP, it can also lower blood pressure throughout the body.
which is a neurological disorder characterized by episodic seizures, affects around 2.3 million Americans, almost half of whom live with uncontrolled seizures. The use of marijuana to treat epilepsy has a complex history. Some animal cases have demonstrated that THC can control seizures that are unresponsive to other treatments, whereas a few have also shown that it might trigger seizures. So far, there exists only one published human clinical trial demonstrating the effectiveness of marijuana in the treatment of epilepsy which was conducted in 1980 and involved only 16 participants. Half of the individuals receiving cannabidiol remained almost free of convulsions throughout the study, and a further 3 demonstrated some improvement in their condition. Only one of the placebo recipients improved.
Recent preclinical studies carried out by the University of Reading identified a particular marijuana compound that showed great promise in the treatment of epilepsy as it helped to reduce convulsions and was well-tolerated. To take this forward, a British pharmaceutical company called GW Pharmaceuticals announced last September that it would be initiating a Phase 1 Clinical Trial of a non-psychoactive cannabinoid called GWP42006 in the treatment of epilepsy.
Anecdotal evidence for the success of marijuana in controlling seizures from epilepsy sufferers also spurred a senator in the U.S. to put forward a bill allowing people in South Carolina to use CBD oil to treat epilepsy, which was passed into law recently.
Muscle Tension and Spasm
It has been suggested that marijuana may be able to help control both muscle stiffness and spasms, but the results are conflicting.
In 2001, a large placebo controlled study was initiated in Britain which set out to investigate marijuana in the treatment of multiple sclerosis. 630 people with different forms of MS were enrolled, and although the study found that oral derivatives or marijuana did not provide objective improvements in spasticity (as measured by physicians), the patients reported feeling improvements in spasticity and pain. Based on these results, a further study was initiated to investigate whether dronabinol ( dronabinol is a synthetic product of Big Pharma ) slows the progression of MS. The study, which was published in lancet Neurology, found that dronabinol did not positively affect (slow) disease progression.
A very recent study, published in the Journal of Biological studies, has suggested that THC can suppress the immune system of rodents through epigenetic modifications (changes in gene expression that do not involve changes in DNA sequence), raising the possibility that it could be used to treat autoimmune diseases such as arthritis and multiple sclerosis. However, it is certainly early yet and further investigation is warranted since the study left many questions unanswered, for example how long the effects of THC last for. Furthermore, their results also hinted that the infamous BRCA2 gene may be suppressed by THC. This is a tumor suppressor gene.
There have been numerous laboratory and animal-based studies that have shown antitumor properties of cannabis, or more specifically THC. In particular, several studies have shown that cannabinoid administration can prevent the growth of cultured brain cancer cells and tumor xenografts (human tumor tissue transplanted into animals) in rodents, including gliomas (brain cancers derived from glial cells). One study investigating the most aggressive glioma, glioblastoma multiforme (GBM), which is also notoriously resistant to anticancer therapies, found that THC in combination with the conventional GBM therapy (temozolomide) exerted strong antitumor activities in mice with glioma xenografts. They also found that administering submaximal doses of THC and cannabidiol, another cannabinoid, together with temozolomide reduced the growth of both temozolomide-sensitive and temozolomide-resistant tumors in animal models.
Although no human studies (in the medical field) have yet been carried out on cancer and cannabis, the promising results gathered so far from cell culture and animal studies prompted researchers to initiate the first human trials using cannabis to treat GBM. The small pilot study will involve a double-blind, randomized placebo-controlled phase with 20 patients investigating cannabinoids in combination with temozolomide. Results, as of this posting date, have not yet been published.
A 2007 Harvard study investigating THC also found that non-toxic doses of the cannabinoid inhibited the growth and spread of lung tumor cell lines and also reduced tumor size in mice with human lung cancer xenografts when compared with a control group. However, the researchers cautioned that they did not know the exact mechanisms behind this and that further investigation is needed since some studies have actually shown that THC can stimulate some cancers. For example, a 2000 study published in the Journal of Immunology found that THC promoted lung tumor growth in mice by impeding the body’s antitumor system.
There are many websites which state that “cannabis cures cancer”- it doesn’t. As demonstrated, cannabis may have many potential applications in medicine, and laboratory and animal studies have yielded some promising results with regards to cancer. But cancer is not one single disease, and saying it is a “cure” is wrong, especially due to conflicting results and the fact that studies so far regarding antitumor properties have not been conducted in humans.
People have been reporting that cannabis is a safe and effective treatment for the symptoms of AIDS, cancer, multiple sclerosis, chronic pain, epilepsy, glaucoma, anxiety disorder, depression, and insomnia.
Not only is medical cannabis showing a great ability to ease the painful symptoms of disease, but it is also showing potential for actually improving health and functionality in its users. Research from the University of Nottingham in the United Kingdom has found that cannabinoids, the chemical compounds found in cannabis, can help to reduce brain damage and improve neurological functioning following a stroke. Another study, from the National Cancer Institute, found that cannabinoids may have a protective effect against the development of certain types of tumors.
The use of medical marijuana has no known severe side-effects. A Canadian study conducted on 215 patients with chronic pain found that after using medical marijuana for one year, patients “had no greater risk than non-users (control group) to experience serious adverse events”. Many people have been using their cannabis card for years and have reported no ill effects, and only positive, life-enhancing results.
Prescription painkillers, on the other hand, seem to be doing a lot of damage to a lot of people.
Prescription painkillers can have a number of adverse side-effects that can lead to severe health complications for users. People have reported side-effects such as liver spots, severe headaches, and bleeding gums. Opioid painkillers can lead to chronic constipation, which can lead to colon cancer down the line.
A 2008 study showed that the common symptoms associated with opioid-based prescription painkillers include “sedation, dizziness, nausea, vomiting, constipation, physical dependence, tolerance, and respiratory depression”. It went on to say that, “Physical dependence and addiction are clinical concerns that may prevent proper prescribing and in turn inadequate pain management. Less common side effects may include delayed gastric emptying, hyperalgesia, immunologic and hormonal dysfunction, muscle rigidity, and myoclonus.” That’s quite a list of negatives!
A recent study has shown that opioid drugs used to relieve pain in cancer patients may stimulate the growth and spread of tumors.
The physical effects of using medical marijuana certainly seem to be safer than asking your doctor to prescribe Liver and Kidney destroying painkillers.
Prescription painkillers can have much worse side-effects than medical marijuana.
Addiction is another major issue. American citizens make up 5% of the world’s population, yet they consume 75% of the world’s prescription drugs. Prescription painkillers can be highly addictive. They are often derived from the same sources as other highly addictive drugs such as heroin and morphine. They are frequently abused by adults and teenagers alike. 54.2% of pain pills in the US are obtained free from a friend or relative.
Tolerance to prescription painkillers tends to build up quickly, so people need to take more and more to get the same effect. The Center for Disease Control and Prevention has declared that prescription drug abuse in the USA is an epidemic. As of 2010, an estimated 52 million Americans over the age of 12 use prescription drugs for non-medical purposes.
Experts believe that the rise in heroin use could be in part due to prescription painkiller abuse. When people become hooked on prescription painkillers, but then can’t get a hold of any, they often turn to heroin. So those people who peddle the old myth that marijuana is a ‘gateway drug’ should be leveling that accusation at prescription painkillers, which have a great deal more in common with harmful and illegal drugs like heroin than cannabis does.
Medical marijuana has proven to be a much more effective remedy than prescription painkillers in a significant number of cases.
Medical cannabis is non-addictive, and there is no evidence that you need to constantly up your dosage due to developing a tolerance to it. People used Medical Marijuana for years at the same levels without needing to up the dose.
With the number of people addicted to painkillers increasing year on year, it is apparent that medical marijuana could provide a valuable and safe treatment alternative.
Both medical cannabis (if it contains THC) and prescription painkillers have potential psychoactive side effects, but the long-term effects of cannabis use seem to be much safer. Studies show that long term opiate use can lead to decreased brain function. Whereas most strains of cannabis, particularly low THC/high CBD strains, appear to have little to no effect on cognitive function at all. So for people suffering from chronic pain, your MM use could offer similar relief to a prescription painkiller but without the negative effects of long-term opiate use on cognitive function.
Deaths caused by prescription drug overdose outnumber deaths caused by heroin and cocaine combined. Every 19 minutes someone dies in the United States of a prescription drug overdose. 17,000 people die of prescription pill overdoses per year. There are zero recorded deaths related to cannabis overdose. Ever. This is a big difference!
The continuous further legalization of Marijuana may be a big factor in a 25% decrease in opiate-related deaths in the states that have legalized mmj so far. That’s a 25% reduction in deaths caused by pain pills, heroin, and morphine.
Pain medication should make your quality of life better, but it seems that a lot of current prescription painkillers in fact make people’s lives worse and shorter. Taking prescription pain-pills can lead to physical dependence and chronic, life-threatening side effects. Medical marijuana is very effective at relieving pain, and is less dangerous than opiates.
So it seems that using Marijuana for medical issues may well be a better option than using prescription pills
Although anecdotal evidence is voluminous -Human trials are required before we can state definitively how useful medical marijuana is in treating each of these and other illnesses.
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Sibinnak Brand (No THC)
Medical Marijuana Tincture